代表性论文

1. Yang Y, Liu B, Xu J, Wang J, Wu J, Shi C, Xu Y, Dong J, Wang C, Lai W, Zhu J, Xiong L, Zhu D, Li X, Yang W, Yamauchi T, Sugawara A, Li Z, Sun F, Li X, Li C, He A, Du Y, Wang T, Zhao C, Li H, Chi X, Zhang H, Liu Y, Li C, Duo S, Yin M, Shen H, Belmonte JCI, Deng H. Derivation of Pluripotent Stem Cells with In Vivo Embryonic and Extraembryonic Potency. Cell. 2017 Apr 6;169(2):243-257.e25.

2. Li X, Liu D, Ma Y, Du X, Jing J, Wang L, Xie B, Sun D, Sun S, Jin X, Zhang X, Zhao T, Guan J, Yi Z, Lai W, Zheng P, Huang Z, Chang Y, Chai Z, Xu J, Deng H. Direct Reprogramming of Fibroblasts via a Chemically Induced XEN-like State. Cell Stem Cell. 2017 Aug 3;21(2):264-273.e7. doi: 10.1016/j.stem.2017.05.019.

3. Li L, Dong J, Yan L, Yong J, Liu X, Hu Y, Fan X, Wu X, Guo H, Wang X, Zhu X, Li R, Yan J, Wei Y, Zhao Y, Wang W, Ren Y, Yuan P, Yan Z, Hu B, Guo F, Wen L, Tang F, Qiao J.  Single-Cell RNA-Seq Analysis Maps Development of Human Germline Cells and Gonadal Niche Interactions. Cell Stem Cell 2017 Jun 1;20(6):858-873

4. Zhu C, Gao Y, Guo H, Xia B, Song J, Wu X, Zeng H, Kee K, Tang F, Yi C. Single-Cell 5-Formylcytosine Landscapes of Mammalian Early Embryos and ESCs at Single-Base Resolution. Cell Stem Cell. 2017 May 4;20(5):720-731

5. Wang Y, Ning X, Gao P, Wu S, Sha M, Lv M, Zhou X, Gao J, Fang R, Meng G, Su X, Jiang Z. (2017) Inflammasome activation triggers caspases-mediated cleavage of cGAS to regulate responses to DNA virus infection. Immunity, 46: 393-404.

6. Qiu WL, Zhang YW, Feng Y, Li LC, Yang L, Xu CR. Deciphering pancreatic islet β-cell and α-cell maturation pathways and characteristic features at the single-cell level. Cell Metabolism, 2017, 25:1194-1205

7. Guo F, Li L, Li J, Wu X, Hu B, Zhu P, Wen L, Tang F. Single-cell multi-omics sequencing of mouse early embryos and embryonic stem cells. Cell Research. 2017 Aug; 27(8):967-988

8. Yang J, Li J, Suzuki K, Liu X, Wu J, Zhang W, Ren R, Zhang W, Chan P, Izpisua Belmonte JC, Qu J, Tang F, Liu GH. Genetic enhancement in cultured human adult stem cells conferred by a single nucleotide recoding. Cell Research. 2017 Sep;27(9):1178-1181

9. Guo H, Hu B, Yan L, Yong J, Wu Y, Gao Y, Guo F, Hou Y, Fan X, Dong J, Wang X, Zhu X, Yan J, Wei Y, Jin H, Zhang W, Wen L, Tang F, Qiao J. DNA methylation and chromatin accessibility profiling of mouse and human fetal germ cells. Cell Research. 2017 Feb;27(2):165-183

10. Yang L, Wang W, Qiu W, Guo Z, Bi E, Xu C. A single-cell tran1111omic analysis reveals precise pathways and regulatory mechanisms underlying hepatoblast differentiation. Hepatology. 2017;66（5）: 1387-1401

11. Huang N, Xia Y, Zhang D, Wang S, Bao Y, He R, Teng J, Chen J.  Hierarchical assembly of centriole subdistal appendages via centrosome binding proteins CCDC120 and CCDC68. Nat Commun. 2017 Apr 19;8:15057.

12. Xu X, Huang S, Zhang B, Huang F, Chi W, Fu J, Wang G, Li S, Jiang Q, Zhang C. DNA replication licensing factor Cdc6 and Plk4 kinase antagonistically regulate centrosome duplication via Sas-6. Nat Commun. 2017 Apr 27;8:15164.

13. Zuo E, Huo X, Yao X, Hu X, Sun Y, Yin J, He B, Wang X, Shi L, Ping J, Wei Y, Ying W, Wei W, Liu W, Tang C, Li Y, Hu J & Yang H. CRISPR/Cas9-mediated targeted chromosome elimination. Genome Biology. 2017.18(1):224. doi: 10.1186/s13059-017-1354-4.

14. Shenoy, T.R., Boysen, G., Wang, M.Y., Xu, Q.Z., Guo, W., Koh, F.M., Wang, C., Zhang, L.Z., Wang, Y., Gil, V., Aziz, S., Christova, R., Rodrigues, D.N., Crespo, M., Rescigno, P., Tunariu, N., Riisnaes, R., Zafeiriou, Z., Flohr, P., Yuan, W., Knight, E., Swain, A., Ramalho-Santos, M., Xu, D.Y., de Bono, J., Wu, H. CHD1 loss sensitizes prostate cancer to DNA damaging therapy by promoting error-prone double-strand break repair. Annals Oncology。 2017 Jul 1;28(7):1495-1507.

15. Liu K, Shen D, Shen JW, Gao SHM, Li B, Wong CI, Feng WD, Song Y. The Super Elongation Complex Drives Neural Stem Cell Fate Commitment。 Developmental Cell。 2017,40(6): 537-551

16. Zhang, Z., Wang, Q., Ke, Y., Liu, S., Ju, J., Lim, A.W., Tang, C., Wei, P. Design of Tunable Oscillatory Dynamics in a Synthetic NF-κB Signaling Circuit. Cell Systems. 2017, 5, 460-470.

17. Xu L, Yang H, Gao Y, Chen Z, Xie L, Liu Y, Liu Y, Wang X, Li H, Lai W, He Y, Yao A, Ma L, Shao Y, Zhang B, Wang C, Chen H, Deng H. CRISPR/Cas9-Mediated CCR5 Ablation in Human Hematopoietic Stem/Progenitor Cells Confers HIV-1 Resistance In Vivo. Mol Ther. 2017 Aug 2;25(8):1782-1789..

18. Fang R, Jiang Q, Zhou X, Wang C, Guan Y, Tao J, Xi J, Feng J, Jiang Z*. (2017) MAVS activates TBK1 and IKK through TRAFs in NEMO dependent and independent manner. PLoS Pathogens, 13(11): e1006720. doi: 10.1371/journal.ppat.1006720.

19. Ma F, Hu Y, Ju Y, Jiang Q, Cheng Z, Zhang Q, Sodmergen. A novel tetratricopeptide repeat protein, WHITE TO GREEN1, is required for early chloroplast development and affects RNA editing in chloroplasts. J Exp Bot. 2017 Dec 16;68(21-22):5829-5843.

20. Chen H, Ning X, Jiang Z.  Caspases control antiviral innate immunity. Cellular & Molecular Immunology, 14(9):736-747.Fang R, Lin Y, Zhou X, Wang C, Guan Y, Tao J, Xi J, Feng J, Jiang Z. (2017) NEMO-IKKβ Are Essential for IRF3 and NF-κB Activation in the cGAS-STING Pathway. J Immunology. 2017, 199(9): 3222-3233.

21. Liu J, Zhang C. The equilibrium of ubiquitination and deubiquitination at PLK1 regulates sister chromatid separation. Cell Mol Life Sci. 2017 Jun;74(12):2127-2134.

22. Fang R, Lin Y, Zhou X, Wang C, Guan Y, Tao J, Xi J, Feng J, Jiang Z. NEMO-IKKβ Are Essential for IRF3 and NF-κB Activation in the cGAS-STING Pathway. J Immunology. 2017；199(9): 3222-3233.

23. Tao J, Zhang X, Jin J, Du X, Lian T, Yang J, Zhou X, Jiang Z, Su X, (2017) Non-specific DNA binding by N-terminal domain promotes activation of human cyclic GMP-AMP synthase. J Immunology, 198(9): 3627-3636.

24. Xu S, Xu Y, Chen L, Fang Q, Song S, Chen J, Teng J. RCN1 suppresses ER stress-induced apoptosis via calcium homeostasis and PERK–CHOP signaling Oncogenesis. 2017 Mar 20;6(3):e304.

25. Chen H, Xu X, Wang G, Zhang B, Wang G, Xin G, Liu J, Jiang Q, Zhang H, Zhang C. CDK4 is degraded by APC/C in mitosis and reaccumulates in early G1 phase to initiate a new cell cycle in HeLa cells. J Biol Chem. 2017 Jun 16;292(24):10131-10141.

26. Zhang B, Wang G, Xu X, Yang S, Zhuang T, Wang G, Ren H, Cheng SY, Jiang Q, Zhang C. DAZ-interacting Protein 1 (Dzip1) Phosphorylation by Polo-like Kinase 1 (Plk1) Regulates the Centriolar Satellite Localization of the BBSome Protein during the Cell Cycle. J Biol Chem. 2017 Jan 27;292(4):1351-1360.