JBC以上文章首页共计29篇

1. Wang S, Zheng Y, Li J, Yu Y, Zhang W, Song M, Liu Z, Min Z, Hu H, Jing Y, He X, Sun L, Ma L, Esteban CR, Chan P, Qiao J, Zhou Q, Izpisua Belmonte JC, Qu J, Tang F, Liu GH. Single-Cell Tran1111omic Atlas of Primate Ovarian Aging. Cell. 2020 Feb 6;180(3):585-600.e19. doi: 10.1016/j.cell.2020.01.009. Epub 2020 Jan 30. PMID: 32004457.

2. Zhou Y, Bian S, Zhou X, Cui Y, Wang W, Wen L, Guo L, Fu W, Tang F. Single Cell Multiomics Sequencing Reveals Prevalent Genomic Alterations in Tumor Stromal Cells of Human Colorectal Cancer. Cancer Cell. 2020 Dec 14;38(6):818-828.e5. doi: 10.1016/j.ccell.2020.09.015. Epub 2020 Oct 22. PMID: 33096021.

3. Wang X, Yang L, Wang YC, Xu ZR, Feng Y, Zhang J, Wang Y, Xu CR. Comparative analysis of cell lineage differentiation during hepatogenesis in humans and mice at the single-cell tran1111ome level. Cell Res. 2020 Dec;30(12):1109-1126. doi: 10.1038/s41422-020-0378-6. Epub 2020 Jul 20. PMID: 32690901; PMCID: PMC7784864.

4. Lv M, Chen M, Zhang R, Zhang W, Wang C, Zhang Y, Wei X, Guan Y, Liu J, Feng K, Jing M, Wang X, Liu YC, Mei Q, Han W, Jiang Z. Manganese is critical for antitumor immune responses via cGAS-STING and improves the efficacy of clinical immunotherapy. Cell Res. 2020 Nov;30(11):966-979. doi: 10.1038/s41422-020-00395-4. Epub 2020 Aug 24. PMID: 32839553; PMCID: PMC7785004.

5. Wang Q, Sun D, Liang Z, Wang J, Zhong X, Lyu Y, Cao J, Lin Z, Du Y, Miao Z, Lu S, Li C, Xu J, Shi Y, Deng H. Generation of human hepatocytes from extended pluripotent stem cells. Cell Res. 2020 Sep;30(9):810-813. doi: 10.1038/s41422-020-0293-x. Epub 2020 Mar 9. PMID: 32152419; PMCID: PMC7608418.

6. Cai Y, Zhou H, Zhu Y, Sun Q, Ji Y, Xue A, Wang Y, Chen W, Yu X, Wang L, Chen H, Li C, Luo T, Deng H. Elimination of senescent cells by β-galactosidase- targeted prodrug attenuates inflammation and restores physical function in aged mice. Cell Res. 2020 Jul;30(7):574-589. doi: 10.1038/s41422-020-0314-9. Epub 2020 Apr 27. PMID: 32341413; PMCID: PMC7184167

7. Chen Y, Lyu R, Rong B, Zheng Y, Lin Z, Dai R, Zhang X, Xie N, Wang S, Tang F, Lan F, Tong MH. Refined spatial temporal epigenomic profiling reveals intrinsic connection between PRDM9-mediated H3K4me3 and the fate of double- stranded breaks. Cell Res. 2020 Mar;30(3):256-268. doi: 10.1038/s41422-020-0281-1. Epub 2020 Feb 11. PMID: 32047271; PMCID: PMC7054334.

8. Chen S, Wang J, Ren H, Liu Y, Xiang C, Li C, Lu S, Shi Y, Deng H, Shi X. Hepatic spheroids derived from human induced pluripotent stem cells in bio- artificial liver rescue porcine acute liver failure. Cell Res. 2020 Jan;30(1):95-97. doi: 10.1038/s41422-019-0261-5. Epub 2019 Dec 11. PMID: 31827240; PMCID: PMC6951340.

9. Li L, Li L, Li Q, Liu X, Ma X, Yong J, Gao S, Wu X, Wei Y, Wang X, Wang W, Li R, Yan J, Zhu X, Wen L, Qiao J, Yan L, Tang F. Dissecting the epigenomic dynamics of human fetal germ cell development at single-cell resolution. Cell Res. 2021 Apr;31(4):463-477. doi: 10.1038/s41422-020-00401-9. Epub 2020 Sep 3. PMID: 32884136.

10. Li LC, Wang X, Xu ZR, Wang YC, Feng Y, Yang L, Qiu WL, Yang L, Yu XX, Gu J, Xu CR. Single-cell patterning and axis characterization in the murine and human definitive endoderm. Cell Res. 2021 Mar;31(3):326-344. doi: 10.1038/s41422-020-00426-0. Epub 2020 Oct 26. PMID: 33106598; PMCID: PMC8027174.

11. Li J, Wang R, Zhou X, Wang W, Gao S, Mao Y, Wu X, Guo L, Liu H, Wen L, Fu W, Tang F. Genomic and tran1111omic profiling of carcinogenesis in patients with familial adenomatous polyposis. Gut. 2020 Jul;69(7):1283-1293. doi: 10.1136/gutjnl-2019-319438. Epub 2019 Nov 19. PMID: 31744909; PMCID: PMC7306982.

12. Fan X, Fu Y, Zhou X, Sun L, Yang M, Wang M, Chen R, Wu Q, Yong J, Dong J, Wen L, Qiao J, Wang X, Tang F. Single-cell tran1111ome analysis reveals cell lineage specification in temporal-spatial patterns in human cortical development. Sci Adv. 2020 Aug 21;6(34): eaaz2978. doi: 10.1126/sciadv.aaz2978. PMID: 32923614; PMCID: PMC7450478.

13. Zhang S, Cui Y, Ma X, Yong J, Yan L, Yang M, Ren J, Tang F, Wen L, Qiao J. Single-cell tran1111omics identifies divergent developmental lineage trajectories during human pituitary development. Nat Commun. 2020 Oct 19;11(1):5275. doi: 10.1038/s41467-020-19012-4. PMID: 33077725; PMCID: PMC7572359.

14. Cheng J, Huang Y, Zhang X, Yu Y, Wu S, Jiao J, Tran L, Zhang W, Liu R, Zhang L, Wang M, Wang M, Yan W, Wu Y, Chi F, Jiang P, Zhang X, Wu H. TRIM21 and PHLDA3 negatively regulate the crosstalk between the PI3K/AKT pathway and PPP metabolism. Nat Commun. 2020 Apr 20;11(1):1880. doi: 10.1038/s41467-020-15819-3. PMID: 32312982; PMCID: PMC7170963.

15. Guan Y, Zhang C, Lyu G, Huang X, Zhang X, Zhuang T, Jia L, Zhang L, Zhang C, Li C, Tao W. Senescence-activated enhancer landscape orchestrates the senescence-associated secretory phenotype in murine fibroblasts. Nucleic Acids Res. 2020 Nov 4;48(19):10909-10923. doi: 10.1093/nar/gkaa858. PMID: 33045748; PMCID: PMC7641768.

16. Jiang Y, Huang J, Lun K, Li B, Zheng H, Li Y, Zhou R, Duan W, Wang C, Feng Y, Yao H, Li C, Ji X. Genome-wide analyses of chromatin interactions after the loss of Pol I, Pol II, and Pol III. Genome Biol. 2020 Jul 2;21(1):158. doi: 10.1186/s13059-020-02067-3. PMID: 32616013; PMCID: PMC7331254.

17. Wang S, Zheng Y, Li Q, He X, Ren R, Zhang W, Song M, Hu H, Liu F, Sun G, Sun S, Liu Z, Yu Y, Chan P, Zhao GG, Zhou Q, Liu GH, Tang F, Qu J. Deciphering primate retinal aging at single-cell resolution. Protein Cell. 2020 Oct 14. doi: 10.1007/s13238-020-00791-x. Epub ahead of print. PMID: 33051815.

18. Liu X, Shen J, Xie L, Wei Z, Wong C, Li Y, Zheng X, Li P, Song Y. Mitotic Implantation of the Tran1111ion Factor Prospero via Phase Separation Drives Terminal Neuronal Differentiation. Dev Cell. 2020 Feb 10;52(3):277-293.e8. doi: 10.1016/j.devcel.2019.11.019. Epub 2019 Dec 19. PMID: 31866201.

19. Lin Q, Yu B, Wang X, Zhu S, Zhao G, Jia M, Huang F, Xu N, Ren H, Jiang Q, Zhang C. K6-linked SUMOylation of BAF regulates nuclear integrity and DNA replication in mammalian cells. Proc Natl Acad Sci U S A. 2020 May 12;117(19):10378-10387. doi: 10.1073/pnas.1912984117. Epub 2020 Apr 24. PMID: 32332162; PMCID: PMC7229763.

20. Wu J, Han X, Zhai H, Yang T, Lin Y. Evidence for rate-dependent filtering of global extrinsic noise by biochemical reactions in mammalian cells. Mol Syst Biol. 2020 May;16(5):e9335. doi: 10.15252/msb.20199335. PMID: 32407587; PMCID: PMC7224485.

21. Liu M, Liu A, Wang J, Zhang Y, Li Y, Su Y, Zhu AJ. Competition between two phosphatases fine-tunes Hedgehog signaling. J Cell Biol. 2021 Feb 1;220(2):e202010078. doi: 10.1083/jcb.202010078. PMID: 33373452; PMCID: PMC7774589.

22. Chi W, Wang G, Xin G, Jiang Q, Zhang C. PLK4-phosphorylated NEDD1 facilitates cartwheel assembly and centriole biogenesis initiations. J Cell Biol. 2021 Jan 4; 220(1): e202002151. doi: 10.1083/jcb.202002151. PMID: 33351100; PMCID: PMC7759300.

23. Deng C, Zhao J, Zhou S, Dong J, Cao J, Gao J, Bai Y, Deng H. The Vascular Disrupting Agent CA4P Improves the Antitumor Efficacy of CAR-T Cells in Preclinical Models of Solid Human Tumors. Mol Ther. 2020 Jan 8;28(1):75-88. doi: 10.1016/j.ymthe.2019.10.010. Epub 2019 Oct 18. PMID: 31672285; PMCID: PMC6953963.

24. Zhao Z, Ma Z, Wang B, Guan Y, Su XD, Jiang Z. Mn 2+ Directly Activates cGAS and Structural Analysis Suggests Mn 2+ Induces a Noncanonical Catalytic Synthesis of 2`3`-cGAMP. Cell Rep. 2020 Aug 18;32(7):108053. doi: 10.1016/j.celrep.2020.108053. PMID: 32814054.

25. Feng S, Wu J, Qiu WL, Yang L, Deng X, Zhou Y, Chen Y, Li X, Yu L, Li H, Xu ZR, Xiao Y, Ren X, Zhang L, Wang C, Sun Z, Wang J, Ding X, Chen Y, Gadue P, Pan G, Ogawa M, Ogawa S, Na J, Zhang P, Hui L, Yin H, Chen L, Xu CR, Cheng X. Large- scale Generation of Functional and Transplantable Hepatocytes and Cholangiocytes from Human Endoderm Stem Cells. Cell Rep. 2020 Dec 8;33(10):108455. doi: 10.1016/j.celrep.2020.108455. PMID: 33296648.

26. Gao Y, Li L, Yuan P, Zhai F, Ren Y, Yan L, Li R, Lian Y, Zhu X, Wu X, Kee K, Wen L, Qiao J, Tang F. 5-Formylcytosine landscapes of human preimplantation embryos at single-cell resolution. PLoS Biol. 2020 Jul 30;18(7): e3000799. doi: 10.1371/journal.pbio.3000799. PMID: 32730243; PMCID: PMC7419013.

27. Feng Y, Qiu WL, Yu XX, Zhang Y, He MY, Li LC, Yang L, Zhang W, Franti M, Ye J, Hoeck JD, Xu CR. Characterizing pancreatic β-cell heterogeneity in the streptozotocin model by single-cell tran1111omic analysis. Mol Metab. 2020 Jul; 37:100982. Doi: 10.1016/j.molmet. 2020.100982. Epub 2020 Apr 2. PMID: 32247924; PMCID: PMC7184252.

28. Yang B, Li B, Jia L, Jiang Y, Wang X, Jiang S, Du S, Ji X, Yang P. 3D landscape of Hepatitis B virus interactions with human chromatins. Cell Discov. 2020 Dec 29;6(1):95. doi: 10.1038/s41421-020-00218-1. PMID: 33372176; PMCID: PMC7769987.

29. Xin G, Fu J, Luo J, Deng Z, Jiang Q, Zhang C. Aurora B regulates PP1γ-Repo- Man interactions to maintain the chromosome condensation state. J Biol Chem. 2020 Oct 23;295(43):14780-14788. doi: 10.1074/jbc.AC120.012772. Epub 2020 Sep 16. PMID: 32938714; PMCID: PMC7586216.